Pseudomonas aeruginosa LESB58, PALES_44731

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_44731
Name
Replicon chromosome
Genomic location 4914584 - 4916596 (+ strand)

Cross-References

RefSeq YP_002442057
GI 218893188
Entrez 7178490

Product

Feature Type CDS
Coding Frame 1
Product Name
alkaline ceramidase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -5.76
Kyte-Doolittle Hydrophobicity Value -0.262
Molecular Weight (kDa) 73.3
Isoelectric Point (pI) 6.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2ZWS HYDROLASE 12/17/08 Crystal Structure Analysis of neutral ceramidase from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.4 X-RAY DIFFRACTION 99.8
2ZXC HYDROLASE 12/22/08 Ceramidase complexed with C2 Pseudomonas aeruginosa 2.2 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 40 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000812 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_44731

Human Homologs

Ensembl 110, assembly GRCh38.p14
N-acylsphingosine amidohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:18860]
E-value: 1.9e-118
Percent Identity: 36.2
Ensembl 110, assembly GRCh38.p14
N-acylsphingosine amidohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:18860]
E-value: 1.9e-118
Percent Identity: 36.2

References

No references are associated with this feature.