Pseudomonas aeruginosa LESB58, PALES_14791

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_14791
Name
Replicon chromosome
Genomic location 1597940 - 1599928 (- strand)

Cross-References

RefSeq YP_002439083
GI 218890219
Entrez 7176221

Product

Feature Type CDS
Coding Frame 1
Product Name
bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -3.48
Kyte-Doolittle Hydrophobicity Value -0.258
Molecular Weight (kDa) 74.3
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
arnA arnA modifies lipid A with 4-amino-4-deoxy-L-arabinose (Ara4N) which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. arnA is found in E. coli and P. aeruginosa. [PMID:11021929, PMID:15939024] ARO:3002985 protein homolog model Strict 1357.0 99.7 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 651 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002112 (427 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_14791

Human Homologs

Ensembl 110, assembly GRCh38.p14
UDP-glucuronate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:17729]
E-value: 4.3e-27
Percent Identity: 27.4
Ensembl 110, assembly GRCh38.p14
UDP-glucuronate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:17729]
E-value: 4.3e-27
Percent Identity: 27.4

References

No references are associated with this feature.