Pseudomonas aeruginosa LES_CF_sputum_CF03_contigs_26_a1, TC72_RS04075
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa LES_CF_sputum_CF03_contigs_26_a1
GCF_000824185.1|latest |
| Locus Tag |
TC72_RS04075
|
| Name |
|
| Replicon | contig_3 |
| Genomic location | 88689 - 88850 (- strand) |
Cross-References
| RefSeq | WP_003100689.1 |
| GI | 489191331 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
MexR antirepressor ArmR
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 4.22 |
| Kyte-Doolittle Hydrophobicity Value | -1.160 |
| Molecular Weight (kDa) | 6.1 |
| Isoelectric Point (pI) | 10.72 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| ArmR | ArmR, a 53-amino-acid antirepressor, allosterically inhibits MexR dimer-DNA binding by occupying a hydrophobic binding cavity within the center of the MexR dimer. ArmR up-regulation and MexR-ArmR complex formation have previously been shown to upregulate MexAB-OprM. [PMID:17545281, PMID:18812515] | ARO:3004056 | protein homolog model | Perfect | 106.3 | 100.0 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 3ECH | Transcription, Transcription regulation | 08/30/08 | The MarR-family repressor MexR in complex with its antirepressor ArmR | Pseudomonas aeruginosa | 1.802 | X-RAY DIFFRACTION | 100.0 |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG001964 (205 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: TC72_RS04075
Search term: MexR antirepressor ArmR
|
Human Homologs
References
No references are associated with this feature.