Pseudomonas aeruginosa PAO581, M801_1854 (clpP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO581 - Assembly GCF_000468555.2
GCF_000468555.2|latest
Locus Tag
M801_1854
Name
clpP
Replicon chromosome
Genomic location 1953949 - 1954590 (+ strand)

Cross-References

RefSeq YP_008557683.1
GI 651863896
EC Number 3.4.21.92
Entrez 19599862

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP-dependent Clp endopeptidase, proteolytic subunit ClpP
Synonyms
Evidence for Translation
Charge (pH 7) -2.42
Kyte-Doolittle Hydrophobicity Value 0.008
Molecular Weight (kDa) 23518.0
Isoelectric Point (pI) 6.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7M1M HYDROLASE 03/13/21 Crystal structure of Pseudomonas aeruginosa ClpP1 Pseudomonas aeruginosa 2.6 X-RAY DIFFRACTION 99.5

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003596 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: M801_1854
Search term: clpP

Human Homologs

Ensembl 110, assembly GRCh38.p14
caseinolytic mitochondrial matrix peptidase proteolytic subunit [Source:HGNC Symbol;Acc:HGNC:2084]
E-value: 8.9e-59
Percent Identity: 58.5

References

No references are associated with this feature.