Pseudomonas putida NBRC 14164, PP4_12970 (gbuA)

Gene Feature Overview

Strain	Pseudomonas putida NBRC 14164 - Assembly GCF_000412675.1 GCF_000412675.1|latest
Locus Tag	PP4_12970
Name	gbuA
Replicon	chromosome
Genomic location	1515264 - 1516214 (- strand)

Cross-References

RefSeq	YP_008112334.1
GI	512684354
Entrez	16134576
INSDC	BAN53150.1
UniParc	UPI0003155191
UniProtKB Acc	T2H2I8
UniProtKB ID	T2H2I8_PSEPU
UniRef100	UniRef100_T2H2I8
UniRef50	UniRef50_Q9I3S3
UniRef90	UniRef90_Q9I3S3

Product

Feature Type	CDS
Coding Frame	1
Product Name	guanidinobutyrase
Synonyms
Evidence for Translation
Charge (pH 7)	-10.26
Kyte-Doolittle Hydrophobicity Value	-0.006
Molecular Weight (kDa)	34.4
Isoelectric Point (pI)	5.34

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3NIO	HYDROLASE	06/16/10	Crystal structure of Pseudomonas aeruginosa guanidinobutyrase	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	90.3

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 434 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001341 (475 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PP4_12970 Search term: gbuA Search term: guanidinobutyrase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000364986 agmatinase [Source:HGNC Symbol;Acc:HGNC:18407] E-value: 2.0e-115 Percent Identity: 63.1

References