Pseudomonas aeruginosa AZPAE14842, NR60_RS10080
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa AZPAE14842
GCF_000789625.1|latest |
| Locus Tag |
NR60_RS10080
|
| Name |
|
| Replicon | contig_12 |
| Genomic location | 385395 - 388166 (- strand) |
Cross-References
| RefSeq | WP_003158825.1 |
| GI | 489250753 |
| NCBI Locus Tag | NR60_RS10080 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
DNA gyrase subunit A
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -39.06 |
| Kyte-Doolittle Hydrophobicity Value | -0.243 |
| Molecular Weight (kDa) | 101.1 |
| Isoelectric Point (pI) | 4.63 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones | Point mutation of Pseudomonas aeruginosa gyrA resulted in the lowered affinity between fluoroquinolones and gyrA. Thus, conferring resistance. [PMID:22821356, PMID:8540700] | ARO:3003684 | protein variant model | T83I, D87N | Strict | 1748.0 | 99.78 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG002447 (536 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: NR60_RS10080
Search term: DNA gyrase subunit A
|
Human Homologs
References
No references are associated with this feature.