Pseudomonas aeruginosa 2192, PA2G_00901

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa 2192
GCF_000152545.1|latest
Locus Tag
PA2G_00901
Name
Replicon chromosome
Genomic location 967830 - 969509 (+ strand)

Cross-References

RefSeq ZP_04933580.1
GI 254240258
NCBI Locus Tag PA2G_00901
UniProtKB Acc A3L874
UniProtKB ID A3L874_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
nuclease
Synonyms
Evidence for Translation
Charge (pH 7) -12.02
Kyte-Doolittle Hydrophobicity Value -0.301
Molecular Weight (kDa) 64.6
Isoelectric Point (pI) 5.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5Y7Q HYDROLASE/DNA 08/17/17 Crystal structure of paFAN1 bound to 2nt 5'flap DNA with gap Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT 2.7 X-RAY DIFFRACTION 99.6
4R8A Hydrolase/DNA 08/30/14 Crystal structure of paFAN1 - 5' flap DNA complex Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT 3.2 X-RAY DIFFRACTION 99.6
5Z6W HYDROLASE/DNA 01/25/18 Crystal structure of paFAN1 bound to 2nt 5'flap DNA with gap with Manganese Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT 3.2 X-RAY DIFFRACTION 99.6
5Y7G HYDROLASE/DNA 08/17/17 Crystal structure of paFAN1 bound to 1nt 5'flap DNA with gap Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT 3.4 X-RAY DIFFRACTION 99.6
4R89 Hydrolase/DNA 08/30/14 Crystal structure of paFAN1 - 5' flap DNA complex with Manganase Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT 4.002 X-RAY DIFFRACTION 99.6

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003538 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2G_00901
Search term: nuclease

Human Homologs

Ensembl 110, assembly GRCh38.p14
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value: 7.6e-17
Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value: 7.6e-17
Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value: 7.6e-17
Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value: 7.6e-17
Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value: 7.6e-17
Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value: 7.6e-17
Percent Identity: 32.3

References

No references are associated with this feature.