Pseudomonas protegens Pf-5, PFL_3372 (hpaE)

Gene Feature Overview

Strain	Pseudomonas protegens Pf-5 GCF_000012265.1|latest
Locus Tag	PFL_3372
Name	hpaE
Replicon	chromosome
Genomic location	3893100 - 3894560 (+ strand)

Cross-References

RefSeq	YP_260477.1
GI	70730736
EC Number	1.2.1.60
Entrez	3476148
INSDC	AAY92641.1
NCBI Locus Tag	PFL_3372
UniParc	UPI000054D832
UniProtKB Acc	Q4KBA6
UniProtKB ID	Q4KBA6_PSEF5
UniRef100	UniRef100_Q4KBA6
UniRef50	UniRef50_Q5SJP9
UniRef90	UniRef90_Q4KBA6

Product

Feature Type	CDS
Coding Frame	1
Product Name	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-5.52
Kyte-Doolittle Hydrophobicity Value	-0.071
Molecular Weight (kDa)	52827.9
Isoelectric Point (pI)	6.15

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 607 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001576 (596 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFL_3372 Search term: hpaE Search term: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000265605 aldehyde dehydrogenase 8 family member A1 [Source:HGNC Symbol;Acc:HGNC:15471] E-value: 2.2e-108 Percent Identity: 40.5

References