Pseudomonas aeruginosa 2192, PA2G_00630

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_00630
Name
Replicon	chromosome
Genomic location	677285 - 678046 (+ strand)

Cross-References

RefSeq	ZP_04933318.1
GI	254239996
NCBI Locus Tag	PA2G_00630
UniProtKB Acc	A3LAL3
UniProtKB ID	A3LAL3_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	short-chain dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.44
Kyte-Doolittle Hydrophobicity Value	0.371
Molecular Weight (kDa)	25.8
Isoelectric Point (pI)	5.76

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
7DJS	OXIDOREDUCTASE	11/21/20	Crystal structure of isopiperitenol dehydrogenase from Pseudomonas aeruginosa complexed with NAD	Pseudomonas aeruginosa	1.7	X-RAY DIFFRACTION	99.6

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000180 (2633 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_00630 Search term: short-chain dehydrogenase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000518355 dehydrogenase/reductase 4 [Source:HGNC Symbol;Acc:HGNC:16985] E-value: 9.1e-26 Percent Identity: 33.9
Ensembl 110, assembly GRCh38.p14	ENSP00000326219 dehydrogenase/reductase 4 [Source:HGNC Symbol;Acc:HGNC:16985] E-value: 9.1e-26 Percent Identity: 33.9

References