Pseudomonas aeruginosa AZPAE14557, NQ81_RS08620

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa AZPAE14557
GCF_000794445.1|latest
Locus Tag
NQ81_RS08620
Name
Replicon contig_8
Genomic location 68576 - 68737 (+ strand)

Cross-References

RefSeq WP_034062146.1
GI 730643488
NCBI Locus Tag NQ81_RS08620

Product

Feature Type CDS
Coding Frame 1
Product Name
antirepressor
Synonyms
Evidence for Translation
Charge (pH 7) 4.22
Kyte-Doolittle Hydrophobicity Value -1.045
Molecular Weight (kDa) 6.1
Isoelectric Point (pI) 10.72

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
ArmR ArmR, a 53-amino-acid antirepressor, allosterically inhibits MexR dimer-DNA binding by occupying a hydrophobic binding cavity within the center of the MexR dimer. ArmR up-regulation and MexR-ArmR complex formation have previously been shown to upregulate MexAB-OprM. [PMID:17545281, PMID:18812515] ARO:3004056 protein homolog model Strict 100.9 96.23 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3ECH Transcription, Transcription regulation 08/30/08 The MarR-family repressor MexR in complex with its antirepressor ArmR Pseudomonas aeruginosa 1.802 X-RAY DIFFRACTION 96.0

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001964 (205 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: NQ81_RS08620
Search term: antirepressor

Human Homologs

References

No references are associated with this feature.