Pseudomonas stutzeri DSM 4166, PSTAA_4220 (pepP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas stutzeri DSM 4166
GCF_000195105.1|latest
Locus Tag
PSTAA_4220
Name
pepP
Replicon chromosome
Genomic location 4546321 - 4547655 (- strand)

Cross-References

RefSeq YP_005940817.1
GI 386022792
Entrez 12531372
INSDC AEA86075.1
NCBI Locus Tag PSTAA_4220
UniParc UPI00020475B3
UniProtKB Acc F2MUR8
UniProtKB ID F2MUR8_PSEU6
UniRef100 UniRef100_F2MUR8
UniRef50 UniRef50_Q2KVZ5
UniRef90 UniRef90_W6RAK0

Product

Feature Type CDS
Coding Frame 1
Product Name
aminopeptidase P
Synonyms
Evidence for Translation
Charge (pH 7) -14.52
Kyte-Doolittle Hydrophobicity Value -0.315
Molecular Weight (kDa) 49.6
Isoelectric Point (pI) 5.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
Apstatin DB04092 DrugBank 5.1.4 P15034 Xaa-Pro aminopeptidase 49.2 443 5.3e-117

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 642 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004805 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSTAA_4220
Search term: pepP
Search term: aminopeptidase P

Human Homologs

Ensembl 110, assembly GRCh38.p14
X-prolyl aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:28052]
E-value: 2.0e-76
Percent Identity: 35.8

References

No references are associated with this feature.