Pseudomonas aeruginosa RP73, M062_15870

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa RP73
GCF_000414035.1|latest
Locus Tag
M062_15870
Name
Replicon chromosome
Genomic location 3409230 - 3410474 (- strand)

Cross-References

RefSeq YP_008133597.1
GI 514410233
Entrez 15960915
NCBI Locus Tag M062_15870

Product

Feature Type CDS
Coding Frame 1
Product Name
3-oxoacyl-ACP synthase
Synonyms
Evidence for Translation
Charge (pH 7) -6.74
Kyte-Doolittle Hydrophobicity Value -0.029
Molecular Weight (kDa) 43.5
Isoelectric Point (pI) 5.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4JPF TRANSFERASE 03/19/13 Structure of wild type Pseudomonas aeruginosa FabF (KASII) in Complex with ligand Pseudomonas aeruginosa 1.67 X-RAY DIFFRACTION 100.0
7OC0 ANTIBIOTIC 04/25/21 Structure of Pseudomonas aeruginosa FabF mutant C164Q in complex with a ligand (2S,4R)-2-(thiophen-2-yl)thiazolidine-4-carboxylic acid Pseudomonas aeruginosa PAO1 1.78 X-RAY DIFFRACTION 99.8
7OC1 ANTIBIOTIC 04/25/21 Structure of Pseudomonas aeruginosa FabF mutant C164Q in complex with Platensimycin Pseudomonas aeruginosa 1.8 X-RAY DIFFRACTION 99.8
4B7V TRANSFERASE 08/22/12 Structure of wild type Pseudomonas aeruginosa FabF (KASII) PSEUDOMONAS AERUGINOSA 1.73 X-RAY DIFFRACTION 100.0
4JB6 TRANSFERASE 02/19/13 Structure of Pseudomonas aeruginosa FabF mutant C164Q Pseudomonas aeruginosa 2.4 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 572 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002617 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: M062_15870

Human Homologs

Ensembl 110, assembly GRCh38.p14
3-oxoacyl-ACP synthase, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26063]
E-value: 3.2e-97
Percent Identity: 47.4

References

No references are associated with this feature.