Pseudomonas aeruginosa M18, PAM18_4694 (nfxB)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_4694
|
| Name |
nfxB
|
| Replicon | chromosome |
| Genomic location | 5196711 - 5197274 (+ strand) |
Cross-References
| RefSeq | YP_005977276.1 |
| GI | 386060754 |
| Entrez | 12568767 |
| NCBI Locus Tag | PAM18_4694 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
transcriptional regulator NfxB
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -2.90 |
| Kyte-Doolittle Hydrophobicity Value | -0.105 |
| Molecular Weight (kDa) | 21.1 |
| Isoelectric Point (pI) | 6.42 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| Type A NfxB | Type A NfxB mutants are four to eight times more resistant to ofloxacin, erythromycin, and new zwitterionic cephems, i.e., cefpirome, cefclidin, cefozopran, and cefoselis, than the parent strain, PAO1. nfxB corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: esrC/nfxB) and 2 loci in Pseudomonas aeruginosa LESB58 (gene name: nfxB). [PMID:8849250] | ARO:3004059 | protein overexpression model | Strict | 368.6 | 99.47 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 25 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004257 (359 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_4694
Search term: nfxB
Search term: transcriptional regulator NfxB
|
Human Homologs
References
No references are associated with this feature.