Pseudomonas aeruginosa M18, PAM18_3438 (fabB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_3438
Name
fabB
Replicon chromosome
Genomic location 3826986 - 3828203 (+ strand)

Cross-References

RefSeq YP_005976023.1
GI 386059501
Entrez 12567493
NCBI Locus Tag PAM18_3438

Product

Feature Type CDS
Coding Frame 1
Product Name
3-oxoacyl-ACP synthase
Synonyms
Evidence for Translation
Charge (pH 7) -8.52
Kyte-Doolittle Hydrophobicity Value -0.094
Molecular Weight (kDa) 42.9
Isoelectric Point (pI) 5.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7PPS TRANSFERASE 09/15/21 apo FabB from Pseudomonas aeruginosa with single point mutation C161A Pseudomonas aeruginosa PA14 1.3 X-RAY DIFFRACTION 99.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 572 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003761 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_3438
Search term: fabB

Human Homologs

Ensembl 110, assembly GRCh38.p14
3-oxoacyl-ACP synthase, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26063]
E-value: 5.5e-57
Percent Identity: 35.0

References

No references are associated with this feature.