Pseudomonas aeruginosa M18, PAM18_3246

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_3246
Name
Replicon chromosome
Genomic location 3628040 - 3629326 (+ strand)

Cross-References

RefSeq YP_005975831.1
GI 386059309
Entrez 12567297
NCBI Locus Tag PAM18_3246

Product

Feature Type CDS
Coding Frame 1
Product Name
putative two-component sensor
Synonyms
Evidence for Translation
Charge (pH 7) -12.17
Kyte-Doolittle Hydrophobicity Value -0.162
Molecular Weight (kDa) 48.4
Isoelectric Point (pI) 5.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
ParS ParS is the sensor component of the two-component ParRS system. Alongside its counterpart ParR, it confers resistance to polycationic antibiotics though regulation of efflux pumps and porins. [PMID:18978025, PMID:21149619, PMID:10984043, PMID:15608211] ARO:3005067 protein homolog model Strict 826.2 99.77 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 622 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003599 (458 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_3246

Human Homologs

References

No references are associated with this feature.