Pseudomonas aeruginosa M18, PAM18_0283 (gpuA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_0283
Name
gpuA
Replicon chromosome
Genomic location 316376 - 317332 (+ strand)

Cross-References

RefSeq YP_005972874.1
GI 386056352
Entrez 12564301
NCBI Locus Tag PAM18_0283

Product

Feature Type CDS
Coding Frame 1
Product Name
3-guanidinopropionase
Synonyms
Evidence for Translation
Charge (pH 7) -10.65
Kyte-Doolittle Hydrophobicity Value -0.029
Molecular Weight (kDa) 34.2
Isoelectric Point (pI) 5.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3NIP HYDROLASE 06/16/10 Crystal structure of Pseudomonas aeruginosa guanidinopropionase complexed with 1,6-diaminohexane Pseudomonas aeruginosa 2.5 X-RAY DIFFRACTION 99.7
3NIQ HYDROLASE 06/16/10 Crystal structure of Pseudomonas aeruginosa guanidinopropionase Pseudomonas aeruginosa 2.07 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 439 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000285 (312 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_0283
Search term: gpuA

Human Homologs

Ensembl 110, assembly GRCh38.p14
agmatinase [Source:HGNC Symbol;Acc:HGNC:18407]
E-value: 3.4e-78
Percent Identity: 46.9

References

No references are associated with this feature.