Pseudomonas aeruginosa PA7, PSPA7_3963 (pfeS)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_3963
Name	pfeS
Replicon	chromosome
Genomic location	4106769 - 4108109 (+ strand)

Cross-References

RefSeq	YP_001349317.1
GI	152987291
Entrez	5354421
INSDC	ABR84474.1
NCBI Locus Tag	PSPA7_3963
UniParc	UPI0000D72975
UniProtKB Acc	A6V8D2
UniProtKB ID	A6V8D2_PSEA7
UniRef100	UniRef100_A6V8D2
UniRef50	UniRef50_Q04804
UniRef90	UniRef90_Q04804

Product

Feature Type	CDS
Coding Frame	1
Product Name	two-component sensor PfeS
Synonyms
Evidence for Translation
Charge (pH 7)	-5.99
Kyte-Doolittle Hydrophobicity Value	-0.242
Molecular Weight (kDa)	50259.9
Isoelectric Point (pI)	6.21

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3KYZ	TRANSFERASE	12/07/09	The crystal structure of the sensor domain of two-component sensor PfeS from Pseudomonas aeruginosa PA01	Pseudomonas aeruginosa	1.497	X-RAY DIFFRACTION	95.9

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 613 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002874 (368 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_3963 Search term: pfeS Search term: two-component sensor PfeS

Human Homologs

References