Pseudomonas aeruginosa PA7, PSPA7_3173 (ligD)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PA7
GCF_000017205.1|latest |
| Locus Tag |
PSPA7_3173
|
| Name |
ligD
|
| Replicon | chromosome |
| Genomic location | 3284226 - 3286769 (- strand) |
Cross-References
| RefSeq | YP_001348533.1 |
| GI | 152983639 |
| Entrez | 5355140 |
| NCBI Locus Tag | PSPA7_3173 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
ATP-dependent DNA ligase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 23.45 |
| Kyte-Doolittle Hydrophobicity Value | -0.525 |
| Molecular Weight (kDa) | 94685.0 |
| Isoelectric Point (pI) | 9.93 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 2FAQ | HYDROLASE/TRANSFERASE | 12/07/05 | Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with ATP and Manganese | Pseudomonas aeruginosa | 1.9 | X-RAY DIFFRACTION | 97.4 |
| 2LJ6 | DNA BINDING PROTEIN | 09/06/11 | Solution Structure and DNA-binding Properties of the Phosphoesterase Domain of DNA Ligase D | Pseudomonas aeruginosa | NOT | SOLUTION NMR | 94.8 |
| 2FAR | Hydrolase/Transferase | 12/07/05 | Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with dATP and Manganese | Pseudomonas aeruginosa | 1.9 | X-RAY DIFFRACTION | 97.4 |
| 2FAO | HYDROLASE/TRANSFERASE | 12/07/05 | Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain | Pseudomonas aeruginosa | 1.5 | X-RAY DIFFRACTION | 97.4 |
| 3N9D | LIGASE | 05/28/10 | Monoclinic Structure of P. aeruginosa LigD phosphoesterase domain | Pseudomonas aeruginosa | 2.3 | X-RAY DIFFRACTION | 94.7 |
| 3N9B | LIGASE | 05/28/10 | Crystal Structure of the P. aeruginosa LigD phosphoesterase domain | Pseudomonas aeruginosa | 1.92 | X-RAY DIFFRACTION | 94.7 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 281 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG003336 (490 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PSPA7_3173
Search term: ligD
Search term: ATP-dependent DNA ligase
|
Human Homologs
References
No references are associated with this feature.