Pseudomonas aeruginosa PA7, PSPA7_1922
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PA7
GCF_000017205.1|latest |
| Locus Tag |
PSPA7_1922
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 1955852 - 1956529 (- strand) |
Cross-References
| RefSeq | YP_001347303.1 |
| GI | 152988873 |
| Entrez | 5354027 |
| NCBI Locus Tag | PSPA7_1922 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
putative two-component response regulator
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -3.65 |
| Kyte-Doolittle Hydrophobicity Value | -0.256 |
| Molecular Weight (kDa) | 24.9 |
| Isoelectric Point (pI) | 5.96 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| Pseudomonas aeruginosa CpxR | CpxR is directly involved in activation of expression of RND efflux pump MexAB-OprM in P. aeruginosa. CpxR is required to enhance mexAB-oprM expression and drug resistance, in the absence of repressor MexR. [PMID:27736975] | ARO:3004054 | protein homolog model | Strict | 440.3 | 98.67 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 622 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG002411 (536 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PSPA7_1922
Search term: putative two-component response regulator
|
Human Homologs
References
No references are associated with this feature.