Pseudomonas aeruginosa PA7, PSPA7_1598 (algL)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_1598
Name	algL
Replicon	chromosome
Genomic location	1628581 - 1629684 (- strand)

Cross-References

RefSeq	YP_001346982.1
GI	152983605
Entrez	5359375
INSDC	ABR80788.1
NCBI Locus Tag	PSPA7_1598
UniParc	UPI0000D72ED1
UniProtKB Acc	A6V1P7
UniProtKB ID	ALGL_PSEA7
UniRef100	UniRef100_A6V1P7
UniRef50	UniRef50_Q9L7P2
UniRef90	UniRef90_Q02R18

Product

Feature Type	CDS
Coding Frame	1
Product Name	poly(beta-D-mannuronate) lyase
Synonyms
Evidence for Translation
Charge (pH 7)	6.33
Kyte-Doolittle Hydrophobicity Value	-0.447
Molecular Weight (kDa)	40.8
Isoelectric Point (pI)	9.01

Subcellular localization

Individual Mappings	Localization Confidence PMID Periplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4OZW	LYASE	02/19/14	Crystal Structure of the periplasmic alginate lyase AlgL H202A mutant	Pseudomonas aeruginosa	1.64	X-RAY DIFFRACTION	97.0
7SA8	LYASE	09/22/21	Crystal Structure of the periplasmic lyase AlgL K66A Mutant	Pseudomonas aeruginosa	2.5	X-RAY DIFFRACTION	96.9
4OZV	LYASE	02/19/14	Crystal Structure of the periplasmic alginate lyase AlgL	Pseudomonas aeruginosa	1.642	X-RAY DIFFRACTION	97.3

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 12 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002119 (490 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_1598 Search term: algL Search term: poly(beta-D-mannuronate) lyase

Human Homologs

References