Pseudomonas aeruginosa PA7, PSPA7_1462

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_1462
Name
Replicon	chromosome
Genomic location	1480466 - 1481569 (+ strand)

Cross-References

RefSeq	YP_001346846.1
GI	152986314
Entrez	5353731
INSDC	ABR83497.1
NCBI Locus Tag	PSPA7_1462
UniParc	UPI0000D730F3
UniProtKB Acc	A6V1B1
UniProtKB ID	A6V1B1_PSEA7
UniRef100	UniRef100_A6V1B1
UniRef50	UniRef50_Q4KHJ5
UniRef90	UniRef90_W0YTY2

Product

Feature Type	CDS
Coding Frame	1
Product Name	RND efflux membrane fusion protein
Synonyms
Evidence for Translation
Charge (pH 7)	6.19
Kyte-Doolittle Hydrophobicity Value	-0.233
Molecular Weight (kDa)	40166.2
Isoelectric Point (pI)	9.83

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
MexJ	MexJ is the membrane fusion protein of the MexJK multidrug efflux protein. [PMID:12193619]	ARO:3003692	protein homolog model		Strict	691.8	98.91	3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 444 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000154 (998 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_1462 Search term: RND efflux membrane fusion protein

Human Homologs

References