Pseudomonas aeruginosa PA7, PSPA7_0999

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_0999
Name
Replicon chromosome
Genomic location 1001292 - 1002017 (- strand)

Cross-References

RefSeq YP_001346385.1
GI 152985092
Entrez 5355412
INSDC ABR82275.1
NCBI Locus Tag PSPA7_0999
UniParc UPI0000D72895
UniProtKB Acc A6V000
UniProtKB ID A6V000_PSEA7
UniRef100 UniRef100_A6V000
UniRef50 UniRef50_T2L7W5
UniRef90 UniRef90_A6V000

Product

Feature Type CDS
Coding Frame 1
Product Name
putative short-chain dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) 0.38
Kyte-Doolittle Hydrophobicity Value 0.123
Molecular Weight (kDa) 25.5
Isoelectric Point (pI) 7.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4AVY OXIDOREDUCTASE 05/30/12 The AEROPATH project and Pseudomonas aeruginosa high-throughput crystallographic studies for assessment of potential targets in early stage drug discovery. PSEUDOMONAS AERUGINOSA PA01 2 X-RAY DIFFRACTION 96.7
4B79 OXIDOREDUCTASE 08/16/12 THE AEROPATH PROJECT AND PSEUDOMONAS AERUGINOSA HIGH-THROUGHPUT CRYSTALLOGRAPHIC STUDIES FOR ASSESSMENT OF POTENTIAL TARGETS IN EARLY STAGE DRUG DISCOVERY. PSEUDOMONAS AERUGINOSA PAO1 1.98 X-RAY DIFFRACTION 96.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000180 (2633 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_0999

Human Homologs

Ensembl 110, assembly GRCh38.p14
carbonyl reductase 4 [Source:HGNC Symbol;Acc:HGNC:25891]
E-value: 2.1e-24
Percent Identity: 36.8

References

No references are associated with this feature.