Pseudomonas aeruginosa UCBPP-PA14, PA14_62280 (hmuV)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_62280
Name	hmuV
Replicon	chromosome
Genomic location	5557200 - 5557967 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	4 transposon mutants in orthologs

Cross-References

RefSeq	YP_793169.1
GI	116052852
Entrez	4385030
INSDC	ABJ14088.1
NCBI Locus Tag	PA14_62280
UniParc	UPI00000D4299
UniProtKB Acc	Q02FW7
UniProtKB ID	HMUV_PSEAB
UniRef100	UniRef100_Q02FW7
UniRef50	UniRef50_Q02FW7
UniRef90	UniRef90_Q02FW7

Product

Feature Type	CDS
Coding Frame	1
Product Name	hemin importer ATP-binding subunit
Synonyms
Evidence for Translation
Charge (pH 7)	-1.65
Kyte-Doolittle Hydrophobicity Value	0.017
Molecular Weight (kDa)	27.5
Isoelectric Point (pI)	6.68

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001543 (890 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_62280 Search term: hmuV Search term: hemin importer ATP-binding subunit

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000442024 ATP binding cassette subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:55] E-value: 1.4e-13 Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14	ENSP00000494751 ATP binding cassette subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:55] E-value: 1.4e-13 Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14	ENSP00000494609 ATP binding cassette subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:55] E-value: 1.4e-13 Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14	ENSP00000495513 ATP binding cassette subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:55] E-value: 1.4e-13 Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14	ENSP00000494431 ATP binding cassette subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:55] E-value: 1.4e-13 Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14	ENSP00000487081 ATP binding cassette subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:55] E-value: 1.4e-13 Percent Identity: 29.9

References