Pseudomonas aeruginosa UCBPP-PA14, PA14_59250 (pilN2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_59250
Name
pilN2
Synonym: type IV b pilus protein
Replicon chromosome
Genomic location 5278639 - 5280276 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_792921.1
GI 116052606
Entrez 4382734
INSDC ABJ13842.1
NCBI Locus Tag PA14_59250
UniParc UPI0000E44BF6
UniProtKB Acc Q02GL5
UniProtKB ID Q02GL5_PSEAB
UniRef100 UniRef100_Q02GL5
UniRef50 UniRef50_Q02GL5
UniRef90 UniRef90_Q02GL5

Product

Feature Type CDS
Coding Frame 1
Product Name
PilN2
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -0.57
Kyte-Doolittle Hydrophobicity Value -0.181
Molecular Weight (kDa) 57999.7
Isoelectric Point (pI) 6.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 115 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG014378 (159 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_59250
Search term: pilN2
Search term: PilN2

Human Homologs

References

The horizontal transfer of Pseudomonas aeruginosa PA14 ICE PAPI-1 is controlled by a transcriptional triad between TprA, NdpA2 and MvaT.
Dangla-Pélissier G, Roux N, Schmidt V, Chambonnier G, Ba M, Sebban-Kreuzer C, de Bentzmann S, Giraud C, Bordi C
Nucleic Acids Res 2021 Nov 8;49(19):10956-10974
PubMed ID: 34643711