Pseudomonas aeruginosa UCBPP-PA14, PA14_57140

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_57140
Name
Replicon chromosome
Genomic location 5089455 - 5090555 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792742.1
GI 116052431
Entrez 4382501
INSDC ABJ13667.1
NCBI Locus Tag PA14_57140
UniParc UPI00000C5CFB
UniProtKB Acc Q02H44
UniProtKB ID Q02H44_PSEAB
UniRef100 UniRef100_W0YZC4
UniRef50 UniRef50_W6R6I9
UniRef90 UniRef90_W0YZC4

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component response regulator
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -5.66
Kyte-Doolittle Hydrophobicity Value -0.033
Molecular Weight (kDa) 40.3
Isoelectric Point (pI) 5.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 585 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003986 (350 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_57140

Human Homologs

References

Sensor kinase PA4398 modulates swarming motility and biofilm formation in Pseudomonas aeruginosa PA14.
Strehmel J, Neidig A, Nusser M, Geffers R, Brenner-Weiss G, Overhage J
Appl Environ Microbiol 2015 Feb;81(4):1274-85
PubMed ID: 25501476