Pseudomonas aeruginosa UCBPP-PA14, PA14_51520 (spcU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_51520
Name
spcU
Replicon chromosome
Genomic location 4580547 - 4580960 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_792284.1
GI 116048915
Entrez 4380010
INSDC ABJ10151.1
NCBI Locus Tag PA14_51520
UniParc UPI00000B3DC5
UniProtKB Acc Q02IF2
UniProtKB ID Q02IF2_PSEAB
UniRef100 UniRef100_Q02IF2
UniRef50 UniRef50_Q02IF2
UniRef90 UniRef90_Q02IF2

Product

Feature Type CDS
Coding Frame 1
Product Name
SpcU
Synonyms
Evidence for Translation
Charge (pH 7) -7.53
Kyte-Doolittle Hydrophobicity Value 0.220
Molecular Weight (kDa) 14.9
Isoelectric Point (pI) 4.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3TU3 TOXIN/TOXIN CHAPERONE 09/15/11 1.92 Angstrom resolution crystal structure of the full-length SpcU in complex with full-length ExoU from the type III secretion system of Pseudomonas aeruginosa Pseudomonas aeruginosa 1.92 X-RAY DIFFRACTION 100.0
4AKX TRANSPORT PROTEIN 02/29/12 Structure of the heterodimeric complex ExoU-SpcU from the type III secretion system (T3SS) of Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 2.94 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG014942 (43 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_51520
Search term: spcU
Search term: SpcU

Human Homologs

References

No references are associated with this feature.