Pseudomonas aeruginosa UCBPP-PA14, PA14_43690 (fabB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_43690
Name
fabB
Replicon chromosome
Genomic location 3890617 - 3891834 (+ strand)

Cross-References

RefSeq YP_791642.1
GI 116049554
EC Number 2.3.1.41
Entrez 4381762
INSDC ABJ10790.1
NCBI Locus Tag PA14_43690
UniParc UPI000045D198
UniProtKB Acc Q02K94
UniProtKB ID FABB_PSEAB
UniRef100 UniRef100_Q02K94
UniRef50 UniRef50_Q02K94
UniRef90 UniRef90_Q02K94

Product

Feature Type CDS
Coding Frame 1
Product Name
3-oxoacyl-ACP synthase
Synonyms
Evidence for Translation
Charge (pH 7) -8.52
Kyte-Doolittle Hydrophobicity Value -0.094
Molecular Weight (kDa) 42.9
Isoelectric Point (pI) 5.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7PPS TRANSFERASE 09/15/21 apo FabB from Pseudomonas aeruginosa with single point mutation C161A Pseudomonas aeruginosa PA14 1.3 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 572 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003761 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_43690
Search term: fabB

Human Homologs

Ensembl 110, assembly GRCh38.p14
3-oxoacyl-ACP synthase, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26063]
E-value: 5.5e-57
Percent Identity: 35.0

References

No references are associated with this feature.