Pseudomonas aeruginosa UCBPP-PA14, PA14_41270

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_41270
Name
Replicon chromosome
Genomic location 3682952 - 3684238 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_791445.1
GI 116049748
Entrez 4383080
INSDC ABJ10984.1
NCBI Locus Tag PA14_41270
UniParc UPI000045D1E1
UniProtKB Acc Q02KU1
UniProtKB ID Q02KU1_PSEAB
UniRef100 UniRef100_Q02KU1
UniRef50 UniRef50_Q9I2U4
UniRef90 UniRef90_Q9I2U4

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component sensor
Synonyms
Evidence for Translation
Charge (pH 7) -12.17
Kyte-Doolittle Hydrophobicity Value -0.162
Molecular Weight (kDa) 48.4
Isoelectric Point (pI) 5.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
ParS ParS is the sensor component of the two-component ParRS system. Alongside its counterpart ParR, it confers resistance to polycationic antibiotics though regulation of efflux pumps and porins. [PMID:18978025, PMID:21149619, PMID:10984043, PMID:15608211] ARO:3005067 protein homolog model Strict 826.2 99.77 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 622 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003599 (458 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_41270

Human Homologs

References

No references are associated with this feature.