Pseudomonas aeruginosa UCBPP-PA14, PA14_40370

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_40370
Name
Replicon	chromosome
Genomic location	3607425 - 3609101 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_791375.1
GI	116049818
Entrez	4385896
INSDC	ABJ11054.1
NCBI Locus Tag	PA14_40370
UniParc	UPI000045D207
UniProtKB Acc	Q02L11
UniProtKB ID	Q02L11_PSEAB
UniRef100	UniRef100_Q02L11
UniRef50	UniRef50_Q9I2N0
UniRef90	UniRef90_Q9I2N0

Product

Feature Type	CDS
Coding Frame	1
Product Name	hypothetical protein
Synonyms
Evidence for Translation
Charge (pH 7)	-11.02
Kyte-Doolittle Hydrophobicity Value	-0.281
Molecular Weight (kDa)	64.5
Isoelectric Point (pI)	5.68

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
5Z6W	HYDROLASE/DNA	01/25/18	Crystal structure of paFAN1 bound to 2nt 5'flap DNA with gap with Manganese	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT	3.2	X-RAY DIFFRACTION	99.3
5Y7G	HYDROLASE/DNA	08/17/17	Crystal structure of paFAN1 bound to 1nt 5'flap DNA with gap	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT	3.4	X-RAY DIFFRACTION	99.3
4R89	Hydrolase/DNA	08/30/14	Crystal structure of paFAN1 - 5' flap DNA complex with Manganase	Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT	4.002	X-RAY DIFFRACTION	99.3
5Y7Q	HYDROLASE/DNA	08/17/17	Crystal structure of paFAN1 bound to 2nt 5'flap DNA with gap	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT	2.7	X-RAY DIFFRACTION	99.3
4R8A	Hydrolase/DNA	08/30/14	Crystal structure of paFAN1 - 5' flap DNA complex	Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT	3.2	X-RAY DIFFRACTION	99.3

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 34 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003538 (532 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_40370

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000499638 FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170] E-value: 5.8e-17 Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14	ENSP00000499703 FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170] E-value: 5.8e-17 Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14	ENSP00000499780 FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170] E-value: 5.8e-17 Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14	ENSP00000354497 FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170] E-value: 5.8e-17 Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14	ENSP00000499534 FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170] E-value: 5.8e-17 Percent Identity: 32.3
Ensembl 110, assembly GRCh38.p14	ENSP00000484956 FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170] E-value: 5.8e-17 Percent Identity: 32.3

References