Pseudomonas aeruginosa UCBPP-PA14, PA14_40120 (polB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_40120
Name
polB
Replicon chromosome
Genomic location 3575143 - 3577506 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_791353.1
GI 116049840
EC Number 2.7.7.7
Entrez 4385606
INSDC ABJ11076.1
NCBI Locus Tag PA14_40120
UniParc UPI00003968C5
UniProtKB Acc Q02L33
UniProtKB ID Q02L33_PSEAB
UniRef100 UniRef100_Q02L33
UniRef50 UniRef50_P21189
UniRef90 UniRef90_Q9I2L1

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA polymerase II
Synonyms
Evidence for Translation
Charge (pH 7) 1.93
Kyte-Doolittle Hydrophobicity Value -0.370
Molecular Weight (kDa) 89.6
Isoelectric Point (pI) 7.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 158 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003524 (528 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_40120
Search term: polB
Search term: DNA polymerase II

Human Homologs

Ensembl 110, assembly GRCh38.p14
DNA polymerase alpha 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9173]
E-value: 1.8e-32
Percent Identity: 25.5
Ensembl 110, assembly GRCh38.p14
DNA polymerase alpha 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9173]
E-value: 1.8e-32
Percent Identity: 25.5

References

No references are associated with this feature.