Pseudomonas aeruginosa UCBPP-PA14, PA14_39980 (qscR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_39980
Name
qscR
Replicon chromosome
Genomic location 3562214 - 3562927 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 8 transposon mutants in orthologs

Cross-References

RefSeq YP_791341.1
GI 116049852
Entrez 4385618
INSDC ABJ11088.1
NCBI Locus Tag PA14_39980
UniParc UPI00000D4284
UniProtKB Acc Q02L45
UniProtKB ID Q02L45_PSEAB
UniRef100 UniRef100_W0YR84
UniRef50 UniRef50_W0YR84
UniRef90 UniRef90_W0YR84

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator
Synonyms
Evidence for Translation
Charge (pH 7) -4.35
Kyte-Doolittle Hydrophobicity Value -0.141
Molecular Weight (kDa) 27.3
Isoelectric Point (pI) 5.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6CBQ transcription/agonist 02/05/18 Crystal structure of QscR bound to agonist S3 Pseudomonas aeruginosa 2.8 X-RAY DIFFRACTION 100.0
3SZT TRANSCRIPTION 07/19/11 Quorum Sensing Control Repressor, QscR, Bound to N-3-oxo-dodecanoyl-L-Homoserine Lactone Pseudomonas aeruginosa 2.55 X-RAY DIFFRACTION 100.0
6CC0 TRANSCRIPTION 02/05/18 Crystal structure of QscR bound to C12-homoserine lactone Pseudomonas aeruginosa 2.5 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 174 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001096 (1439 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_39980
Search term: qscR

Human Homologs

References

No references are associated with this feature.