Pseudomonas aeruginosa UCBPP-PA14, PA14_32650

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_32650
Name
Replicon	chromosome
Genomic location	2835508 - 2836152 (- strand)
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	YP_790764.1
GI	116050417
Entrez	4380557
INSDC	ABJ11653.1
NCBI Locus Tag	PA14_32650
UniParc	UPI0000395DBC
UniProtKB Acc	Q02MS2
UniProtKB ID	Q02MS2_PSEAB
UniRef100	UniRef100_S0I0R0
UniRef50	UniRef50_A0A085A7Q2
UniRef90	UniRef90_W0YUG7

Product

Feature Type	CDS
Coding Frame	1
Product Name	glutathione S-transferase
Synonyms
Evidence for Translation
Charge (pH 7)	0.80
Kyte-Doolittle Hydrophobicity Value	-0.057
Molecular Weight (kDa)	23.9
Isoelectric Point (pI)	7.41

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6JWK	ISOMERASE	04/20/19	Crystal structure of maleylpyruvate isomerase from Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	1.86	X-RAY DIFFRACTION	98.6

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 204 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003079 (825 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_32650 Search term: glutathione S-transferase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000451976 glutathione S-transferase zeta 1 [Source:HGNC Symbol;Acc:HGNC:4643] E-value: 3.7e-36 Percent Identity: 43.3
Ensembl 110, assembly GRCh38.p14	ENSP00000216465 glutathione S-transferase zeta 1 [Source:HGNC Symbol;Acc:HGNC:4643] E-value: 3.7e-36 Percent Identity: 43.3

References