Pseudomonas aeruginosa BWH058, V559_RS0106285

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa BWH058
GCF_000629425.1|latest
Locus Tag
V559_RS0106285
Name
Replicon adTyf-supercont1.1
Genomic location 1388751 - 1388912 (+ strand)

Cross-References

RefSeq WP_003109634.1
GI 489200413
NCBI Locus Tag V559_RS0106285

Product

Feature Type CDS
Coding Frame 1
Product Name
antirepressor
Synonyms
Evidence for Translation
Charge (pH 7) 4.22
Kyte-Doolittle Hydrophobicity Value -1.158
Molecular Weight (kDa) 6.1
Isoelectric Point (pI) 10.72

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
ArmR ArmR, a 53-amino-acid antirepressor, allosterically inhibits MexR dimer-DNA binding by occupying a hydrophobic binding cavity within the center of the MexR dimer. ArmR up-regulation and MexR-ArmR complex formation have previously been shown to upregulate MexAB-OprM. [PMID:17545281, PMID:18812515] ARO:3004056 protein homolog model Strict 105.1 98.11 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3ECH Transcription, Transcription regulation 08/30/08 The MarR-family repressor MexR in complex with its antirepressor ArmR Pseudomonas aeruginosa 1.802 X-RAY DIFFRACTION 100.0

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001964 (205 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: V559_RS0106285
Search term: antirepressor

Human Homologs

References

No references are associated with this feature.