Pseudomonas sp. URMO17WK12:I12, D882_RS0115650

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas sp. URMO17WK12:I12
GCF_000514395.1|latest
Locus Tag
D882_RS0115650
Name
Replicon scaffold00009.9_C
Genomic location 307030 - 308100 (+ strand)

Cross-References

RefSeq WP_027924117.1
GI 654453680
NCBI Locus Tag D882_RS0115650

Product

Feature Type CDS
Coding Frame 1
Product Name
dTDP-glucose 4,6-dehydratase
Synonyms
Evidence for Translation
Charge (pH 7) -12.54
Kyte-Doolittle Hydrophobicity Value -0.485
Molecular Weight (kDa) 40.2
Isoelectric Point (pI) 5.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
2'deoxy-Thymidine-5'-Diphospho-Alpha-D-Glucose DB03751 DrugBank 5.1.4 P26391 dTDP-glucose 4,6-dehydratase 74.4 363 3.5e-159

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004752 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: D882_RS0115650

Human Homologs

Ensembl 110, assembly GRCh38.p14
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value: 4.3e-13
Percent Identity: 27.9
Ensembl 110, assembly GRCh38.p14
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value: 4.3e-13
Percent Identity: 27.9

References

No references are associated with this feature.