Pseudomonas aeruginosa PA1R, PA1R_gp5421
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PA1R
GCF_000496645.1|latest |
| Locus Tag |
PA1R_gp5421
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 6015797 - 6017083 (- strand) |
Cross-References
| RefSeq | YP_008808017.1 |
| GI | 558671307 |
| Entrez | 17681500 |
| NCBI Locus Tag | PA1R_gp5421 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
Sensory histidine kinase in two-component regulatory system with RstA
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -12.17 |
| Kyte-Doolittle Hydrophobicity Value | -0.167 |
| Molecular Weight (kDa) | 48.4 |
| Isoelectric Point (pI) | 5.24 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| ParS | ParS is the sensor component of the two-component ParRS system. Alongside its counterpart ParR, it confers resistance to polycationic antibiotics though regulation of efflux pumps and porins. [PMID:18978025, PMID:21149619, PMID:10984043, PMID:15608211] | ARO:3005067 | protein homolog model | Strict | 825.1 | 99.53 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 622 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG003599 (458 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA1R_gp5421
|
Human Homologs
References
No references are associated with this feature.