Pseudomonas aeruginosa LES431, T223_25455
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa LES431
GCF_000508765.1|latest |
| Locus Tag |
T223_25455
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 5437937 - 5438500 (+ strand) |
Cross-References
| RefSeq | YP_008945110.1 |
| GI | 568156118 |
| Entrez | 17989201 |
| NCBI Locus Tag | T223_25455 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
transcriptional regulator
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -2.90 |
| Kyte-Doolittle Hydrophobicity Value | -0.091 |
| Molecular Weight (kDa) | 21.1 |
| Isoelectric Point (pI) | 6.42 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| Type A NfxB | Type A NfxB mutants are four to eight times more resistant to ofloxacin, erythromycin, and new zwitterionic cephems, i.e., cefpirome, cefclidin, cefozopran, and cefoselis, than the parent strain, PAO1. nfxB corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: esrC/nfxB) and 2 loci in Pseudomonas aeruginosa LESB58 (gene name: nfxB). [PMID:8849250] | ARO:3004059 | protein overexpression model | Strict | 369.8 | 100.0 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 26 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004257 (359 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: T223_25455
Search term: transcriptional regulator
|
Human Homologs
References
No references are associated with this feature.