Pseudomonas aeruginosa LES431, T223_12305

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa LES431
GCF_000508765.1|latest
Locus Tag
T223_12305
Name
Replicon chromosome
Genomic location 2554490 - 2555830 (- strand)

Cross-References

RefSeq YP_008942534.1
GI 568153564
Entrez 17986576
NCBI Locus Tag T223_12305

Product

Feature Type CDS
Coding Frame 1
Product Name
histidine kinase
Synonyms
Evidence for Translation
Charge (pH 7) -11.75
Kyte-Doolittle Hydrophobicity Value -0.241
Molecular Weight (kDa) 50.4
Isoelectric Point (pI) 5.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3KYZ TRANSFERASE 12/07/09 The crystal structure of the sensor domain of two-component sensor PfeS from Pseudomonas aeruginosa PA01 Pseudomonas aeruginosa 1.497 X-RAY DIFFRACTION 98.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 613 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002874 (368 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: T223_12305
Search term: histidine kinase

Human Homologs

References

No references are associated with this feature.