Pseudomonas aeruginosa PAO1, PA5202

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5202
Name
Replicon chromosome
Genomic location 5855936 - 5856325 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253889.1
GI 15600395
Affymetrix PA5202_at
DNASU PaCD00008240
Entrez 878508
GenBank AAG08587.1
INSDC AAG08587.1
NCBI Locus Tag PA5202
protein_id(GenBank) gb|AAG08587.1|AE004933_3|gnl|PseudoCAP|PA5202
TIGR NTL03PA05203
UniParc UPI00000C5F50
UniProtKB Acc Q9HTY7
UniProtKB ID Q9HTY7_PSEAE
UniRef100 UniRef100_Q9HTY7
UniRef50 UniRef50_Q45388
UniRef90 UniRef90_Q9HTY8

Product

Feature Type CDS
Coding Frame 1
Product Name
thiolester hydrolase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 0.86
Kyte-Doolittle Hydrophobicity Value 0.075
Molecular Weight (kDa) 13.8
Isoelectric Point (pI) 7.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1ZKI STRUCTURAL GENOMICS, UNKNOWN FUNCTION 05/02/05 Structure of conserved protein PA5202 from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.7 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 238 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004786 (517 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5202

Human Homologs

References

Structure and activity of the Pseudomonas aeruginosa hotdog-fold thioesterases PA5202 and PA2801.
Gonzalez CF, Tchigvintsev A, Brown G, Flick R, Evdokimova E, Xu X, Osipiuk J, Cuff ME, Lynch S, Joachimiak A, Savchenko A, Yakunin AF
Biochem J 2012 Jun 15;444(3):445-55
PubMed ID: 22439787