Pseudomonas aeruginosa PAO1, PA5148

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5148
Name
Synonym: yggX
Replicon chromosome
Genomic location 5797065 - 5797337 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentThe structure of E. coli YggX displays a fold consisting of two N-terminal antiparallel beta-sheets and three alpha-helices, which shares significant structural similarity to the crystal structure of PA5148

Cross-References

RefSeq NP_253835.1
GI 15600341
Affymetrix PA5148_at
Entrez 878754
GenBank AAG08533.1
INSDC AAG08533.1
NCBI Locus Tag PA5148
protein_id(GenBank) gb|AAG08533.1|AE004927_11|gnl|PseudoCAP|PA5148
TIGR NTL03PA05149
UniParc UPI00000C5F26
UniProtKB Acc Q9HU36
UniProtKB ID FETP_PSEAE
UniRef100 UniRef100_A6VDR9
UniRef50 UniRef50_A6VDR9
UniRef90 UniRef90_A6VDR9

Product

Feature Type CDS
Coding Frame 1
Product Name
putative oxidative stress-related protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -0.56
Kyte-Doolittle Hydrophobicity Value -1.100
Molecular Weight (kDa) 10.6
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1T07 Structural genomics, unknown function 04/07/04 Crystal Structure of Conserved Protein of Unknown Function PA5148 from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.8 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 156 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004742 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5148

Human Homologs

References

The solution structure of the oxidative stress-related protein YggX from Escherichia coli.
Osborne MJ, Siddiqui N, Landgraf D, Pomposiello PJ, Gehring K
Protein Sci 2005 Jun;14(6):1673-8
PubMed ID: 15883188