Pseudomonas aeruginosa PAO1, PA4290

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4290
Name
Replicon chromosome
Genomic location 4812598 - 4814214 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252980.1
GI 15599486
Affymetrix PA4290_at
Entrez 881648
GenBank AAG07678.1
INSDC AAG07678.1
NCBI Locus Tag PA4290
protein_id(GenBank) gb|AAG07678.1|AE004845_4|gnl|PseudoCAP|PA4290
TIGR NTL03PA04291
UniParc UPI00000C5C9B
UniProtKB Acc Q9HWB0
UniProtKB ID Q9HWB0_PSEAE
UniRef100 UniRef100_Q9HWB0
UniRef50 UniRef50_J2Y7K9
UniRef90 UniRef90_Q9HWB0

Product

Feature Type CDS
Coding Frame 1
Product Name
probable chemotaxis transducer
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -13.17
Kyte-Doolittle Hydrophobicity Value -0.219
Molecular Weight (kDa) 58.4
Isoelectric Point (pI) 5.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 398 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003893 (457 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4290

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295