Pseudomonas aeruginosa BWHPSA021, Q034_04346

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa BWHPSA021
GCF_000481285.1|latest
Locus Tag
Q034_04346
Name
Replicon scaffold_1
Genomic location 4708484 - 4710808 (- strand)

Cross-References

RefSeq WP_003146103.1
GI 489237844
NCBI Locus Tag Q034_04346

Product

Feature Type CDS
Coding Frame 1
Product Name
penicillin-binding protein 1B
Synonyms
Evidence for Translation
Charge (pH 7) 11.89
Kyte-Doolittle Hydrophobicity Value -0.282
Molecular Weight (kDa) 85.5
Isoelectric Point (pI) 9.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
Cefpiramide DB00430 DrugBank 5.1.4 Q9X6W0 Penicillin-binding protein 1B 99.9 774 0.0e+00
Ceftazidime DB00438 DrugBank 5.1.4 Q9X6W0 Penicillin-binding protein 1B 99.9 774 0.0e+00
Cefoperazone DB01329 DrugBank 5.1.4 Q9X6W0 Penicillin-binding protein 1B 99.9 774 0.0e+00
Ceftolozane DB09050 DrugBank 5.1.4 Q9X6W0 Penicillin-binding protein 1B 99.9 774 0.0e+00

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004349 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Q034_04346

Human Homologs

References

No references are associated with this feature.