Pseudomonas aeruginosa PAO1, PA4107 (efhP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4107
Name
efhP
Replicon chromosome
Genomic location 4590396 - 4590863 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_252796.1
GI 15599302
Affymetrix PA4107_at
DNASU PaCD00007794
Entrez 877738
GenBank AAG07494.1
INSDC AAG07494.1
NCBI Locus Tag PA4107
protein_id(GenBank) gb|AAG07494.1|AE004827_3|gnl|PseudoCAP|PA4107
TIGR NTL03PA04107
UniParc UPI00000C5C15
UniProtKB Acc Q9HWS1
UniProtKB ID Q9HWS1_PSEAE
UniRef100 UniRef100_Q9HWS1
UniRef50 UniRef50_Q9HWS1
UniRef90 UniRef90_Q9HWS1

Product

Feature Type CDS
Coding Frame 1
Product Name
EfhP
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -4.17
Kyte-Doolittle Hydrophobicity Value -0.379
Molecular Weight (kDa) 15.8
Isoelectric Point (pI) 5.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 9 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005151 (289 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4107
Search term: efhP
Search term: EfhP

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
A Pseudomonas aeruginosa EF-hand protein, EfhP (PA4107), modulates stress responses and virulence at high calcium concentration.
Sarkisova SA, Lotlikar SR, Guragain M, Kubat R, Cloud J, Franklin MJ, Patrauchan MA
PLoS One 2014;9(2):e98985
PubMed ID: 24918783