Pseudomonas aeruginosa PAO1, PA2572

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2572
Name
Replicon chromosome
Genomic location 2907656 - 2908999 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251262.1
GI 15597768
Affymetrix PA2572_at
Entrez 878109
GenBank AAG05960.1
INSDC AAG05960.1
NCBI Locus Tag PA2572
protein_id(GenBank) gb|AAG05960.1|AE004685_6|gnl|PseudoCAP|PA2572
TIGR NTL03PA02572
UniParc UPI00000C5746
UniProtKB Acc Q9I0R4
UniProtKB ID Q9I0R4_PSEAE
UniRef100 UniRef100_W0YTI5
UniRef50 UniRef50_Q4K707
UniRef90 UniRef90_A6V4M1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable two-component response regulator
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -11.18
Kyte-Doolittle Hydrophobicity Value -0.305
Molecular Weight (kDa) 50.8
Isoelectric Point (pI) 5.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database PseudoCAP
Category
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism Galleria mellonella
Notes
Infection model Galleria mellonella killing assay
Reference 19170727

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 607 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002973 (763 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2572

Human Homologs

References

No references are associated with this feature.