Pseudomonas aeruginosa PAO1, PA2354 (sfnR1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2354
Name
sfnR1
Replicon chromosome
Genomic location 2601219 - 2602349 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs
CommentDescribed as Sfa3 in PMID:24204589. According to PseudoCAP conventions, earlier usage of Sfa3 takes precedence over SnfR2 in PMID:30478084.

Cross-References

RefSeq NP_251044.1
GI 15597550
Affymetrix PA2354_at
Entrez 882192
GenBank AAG05742.1
INSDC AAG05742.1
NCBI Locus Tag PA2354
protein_id(GenBank) gb|AAG05742.1|AE004661_9|gnl|PseudoCAP|PA2354
TIGR NTL03PA02354
UniParc UPI00000C5688
UniProtKB Acc Q9I1C4
UniProtKB ID Q9I1C4_PSEAE
UniRef100 UniRef100_Q9I1C4
UniRef50 UniRef50_V5BGH7
UniRef90 UniRef90_Q9I1C4

Product

Feature Type CDS
Coding Frame 1
Product Name
SfnR1
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 5.29
Kyte-Doolittle Hydrophobicity Value -0.231
Molecular Weight (kDa) 41.6
Isoelectric Point (pI) 8.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 450 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003160 (766 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2354
Search term: sfnR1
Search term: SfnR1

Human Homologs

References

SfnR2 Regulates Dimethyl Sulfide-Related Utilization in Pseudomonas aeruginosa PAO1.
Lundgren BR, Sarwar Z, Feldman KS, Shoytush JM, Nomura CT
J Bacteriol 2019 Feb 15;201(4)
PubMed ID: 30478084