Pseudomonas aeruginosa PAO1, PA2233 (pslC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2233
Name
pslC
Replicon chromosome
Genomic location 2456569 - 2457480 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Commentpsl cluster plays a role in cell-cell and/or cell-surface interaction in biofilm formation.

Cross-References

RefSeq NP_250923.1
GI 15597429
Affymetrix PA2233_at
Entrez 878103
GenBank AAG05621.1
INSDC AAG05621.1
NCBI Locus Tag PA2233
protein_id(GenBank) gb|AAG05621.1|AE004649_12|gnl|PseudoCAP|PA2233
TIGR NTL03PA02233
UniParc UPI00000C561F
UniProtKB Acc Q9I1N6
UniProtKB ID Q9I1N6_PSEAE
UniRef100 UniRef100_Q9I1N6
UniRef50 UniRef50_A0A080V0Y2
UniRef90 UniRef90_A0A080V0Y2

Product

Feature Type CDS
Coding Frame 1
Product Name
PslC
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 4.38
Kyte-Doolittle Hydrophobicity Value -0.209
Molecular Weight (kDa) 33.6
Isoelectric Point (pI) 8.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 109 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005118 (370 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2233
Search term: pslC
Search term: PslC

Human Homologs

References

Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2).
Jiang XM, Neal B, Santiago F, Lee SJ, Romana LK, Reeves PR
Mol Microbiol 1991 Mar;5(3):695-713
PubMed ID: 1710759
Identification of a genetic locus essential for serotype b-specific antigen synthesis in Actinobacillus actinomycetemcomitans.
Yoshida Y, Nakano Y, Yamashita Y, Koga T
Infect Immun 1998 Jan;66(1):107-14
PubMed ID: 9423846
Genetic and biochemical analyses of the Pseudomonas aeruginosa Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production.
Byrd MS, Sadovskaya I, Vinogradov E, Lu H, Sprinkle AB, Richardson SH, Ma L, Ralston B, Parsek MR, Anderson EM, Lam JS, Wozniak DJ
Mol Microbiol 2009 Aug;73(4):622-38
PubMed ID: 19659934