Pseudomonas aeruginosa PAO1, PA2132 (cupA5)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2132
Name
cupA5
Replicon chromosome
Genomic location 2347828 - 2348541 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_250822.1
GI 15597328
Affymetrix PA2132_at
Entrez 880865
GenBank AAG05520.1
INSDC AAG05520.1
NCBI Locus Tag PA2132
protein_id(GenBank) gb|AAG05520.1|AE004640_9|gnl|PseudoCAP|PA2132
TIGR NTL03PA02132
UniParc UPI00000C55C2
UniProtKB Acc Q9I1Y3
UniProtKB ID Q9I1Y3_PSEAE
UniRef100 UniRef100_W0YQ75
UniRef50 UniRef50_W0YQ75
UniRef90 UniRef90_W0YQ75

Product

Feature Type CDS
Coding Frame 1
Product Name
chaperone CupA5
Product Name Confidence: Class 1
Synonyms probable pili assembly chaperone
Evidence for Translation
Charge (pH 7) -0.31
Kyte-Doolittle Hydrophobicity Value -0.236
Molecular Weight (kDa) 26.1
Isoelectric Point (pI) 6.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 46 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000956 (1721 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2132
Search term: cupA5
Search term: chaperone CupA5

Human Homologs

References

The chaperone/usher pathways of Pseudomonas aeruginosa: identification of fimbrial gene clusters (cup) and their involvement in biofilm formation.
Vallet I, Olson JW, Lory S, Lazdunski A, Filloux A
Proc Natl Acad Sci U S A 2001 Jun 5;98(12):6911-6
PubMed ID: 11381121