Pseudomonas aeruginosa PAO1, PA2126 (cgrC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2126
Name
cgrC
Replicon chromosome
Genomic location 2339352 - 2339987 (- strand)
Transposon Mutants 7 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250816.1
GI 15597322
Affymetrix PA2126_at
DNASU PaCD00006941
Entrez 878585
GenBank AAG05514.1
INSDC AAG05514.1
NCBI Locus Tag PA2126
protein_id(GenBank) gb|AAG05514.1|AE004640_3|gnl|PseudoCAP|PA2126
TIGR NTL03PA02126
UniParc UPI00000C55BD
UniProtKB Acc Q9I1Y9
UniProtKB ID Q9I1Y9_PSEAE
UniRef100 UniRef100_W0YP76
UniRef50 UniRef50_P77174
UniRef90 UniRef90_W0YP76

Product

Feature Type CDS
Coding Frame 1
Product Name
cupA gene regulator C, CgrC
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 1.89
Kyte-Doolittle Hydrophobicity Value -0.327
Molecular Weight (kDa) 23.7
Isoelectric Point (pI) 7.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 35 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003346 (295 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2126
Search term: cgrC

Human Homologs

References

The CgrA and CgrC proteins form a complex that positively regulates cupA fimbrial gene expression in Pseudomonas aeruginosa.
McManus HR, Dove SL
J Bacteriol 2011 Nov;193(22):6152-61
PubMed ID: 21926232
Local and global regulators linking anaerobiosis to cupA fimbrial gene expression in Pseudomonas aeruginosa.
Vallet-Gely I, Sharp JS, Dove SL
J Bacteriol 2007 Dec;189(23):8667-76
PubMed ID: 17890313