Pseudomonas aeruginosa PAO1, PA2059 (sppB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2059
Name
sppB
Replicon chromosome
Genomic location 2255629 - 2256702 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250749.1
GI 15597255
Affymetrix PA2059_at
DNASU PaCD00006917
Entrez 877721
GenBank AAG05447.1
INSDC AAG05447.1
NCBI Locus Tag PA2059
protein_id(GenBank) gb|AAG05447.1|AE004632_6|gnl|PseudoCAP|PA2059
TIGR NTL03PA02059
UniParc UPI00000C557C
UniProtKB Acc Q9I256
UniProtKB ID Q9I256_PSEAE
UniRef100 UniRef100_Q9I256
UniRef50 UniRef50_E1SAA2
UniRef90 UniRef90_V6AG83

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter permease, SppB
Product Name Confidence: Class 1
Synonyms probable permease of ABC transporter
Evidence for Translation
Charge (pH 7) 2.19
Kyte-Doolittle Hydrophobicity Value 0.591
Molecular Weight (kDa) 38.4
Isoelectric Point (pI) 8.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 582 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003390 (385 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2059
Search term: sppB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Swarming motility is modulated by expression of the putative xenosiderophore transporter SppR-SppABCD in Pseudomonas aeruginosa PA14.
Pletzer D, Braun Y, Weingart H
Antonie Van Leeuwenhoek 2016 Jun;109(6):737-53
PubMed ID: 26995781