Pseudomonas aeruginosa PAO1, PA1979 (eraS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1979
Name
eraS
Synonym: exaD
Replicon chromosome
Genomic location 2165213 - 2165863 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_250669.1
GI 15597175
Affymetrix PA1979_at
DNASU PaCD00006888
Entrez 880447
GenBank AAG05367.1
INSDC AAG05367.1
NCBI Locus Tag PA1979
protein_id(GenBank) gb|AAG05367.1|AE004624_6|gnl|PseudoCAP|PA1979
TIGR NTL03PA01979
UniParc UPI00000C553D
UniProtKB Acc Q9I2C8
UniProtKB ID Q9I2C8_PSEAE
UniRef100 UniRef100_Q9I2C8
UniRef50 UniRef50_Q9I2C8
UniRef90 UniRef90_Q9I2C8

Product

Feature Type CDS
Coding Frame 1
Product Name
sensor kinase, EraS
Product Name Confidence: Class 1
Synonyms ExaD
Evidence for Translation
Charge (pH 7) 4.50
Kyte-Doolittle Hydrophobicity Value -0.325
Molecular Weight (kDa) 23.8
Isoelectric Point (pI) 8.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 412 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003453 (398 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1979
Search term: eraS

Human Homologs

References

Structure and function of the uhp genes for the sugar phosphate transport system in Escherichia coli and Salmonella typhimurium.
Island MD, Wei BY, Kadner RJ
J Bacteriol 1992 May;174(9):2754-62
PubMed ID: 1569007
A soluble two-component regulatory system controls expression of quinoprotein ethanol dehydrogenase (QEDH) but not expression of cytochrome c(550) of the ethanol-oxidation system in Pseudomonas aeruginosa.
Schobert M, Görisch H
Microbiology (Reading) 2001 Feb;147(Pt 2):363-372
PubMed ID: 11158353