Pseudomonas aeruginosa PAO1, PA1869 (acp1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1869
Name
acp1
Replicon chromosome
Genomic location 2031466 - 2031705 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs
Comment

Cross-References

RefSeq NP_250560.1
GI 15597066
Affymetrix PA1869_at
DNASU PaCD00006842
Entrez 881955
GenBank AAG05258.1
INSDC AAG05258.1
NCBI Locus Tag PA1869
protein_id(GenBank) gb|AAG05258.1|AE004613_3|gnl|PseudoCAP|PA1869
TIGR NTL03PA01870
UniParc UPI00001252F2
UniProtKB Acc O52658
UniProtKB ID ACP2_PSEAE
UniRef100 UniRef100_O52658
UniRef50 UniRef50_O52658
UniRef90 UniRef90_O52658

Product

Feature Type CDS
Coding Frame 1
Product Name
Acp1
Product Name Confidence: Class 1
Synonyms probable acyl carrier protein
Evidence for Translation
Charge (pH 7) -15.03
Kyte-Doolittle Hydrophobicity Value -0.176
Molecular Weight (kDa) 9.0
Isoelectric Point (pI) 3.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 532 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003534 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1869
Search term: acp1
Search term: Acp1

Human Homologs

Ensembl 110, assembly GRCh38.p14
NADH:ubiquinone oxidoreductase subunit AB1 [Source:HGNC Symbol;Acc:HGNC:7694]
E-value: 6.6e-07
Percent Identity: 33.3
Ensembl 110, assembly GRCh38.p14
NADH:ubiquinone oxidoreductase subunit AB1 [Source:HGNC Symbol;Acc:HGNC:7694]
E-value: 6.6e-07
Percent Identity: 33.3

References

Bacillus subtilis acyl carrier protein is encoded in a cluster of lipid biosynthesis genes.
Morbidoni HR, de Mendoza D, Cronan JE Jr
J Bacteriol 1996 Aug;178(16):4794-800
PubMed ID: 8759840
Acyl Carrier Protein 3 Is Involved in Oxidative Stress Response in Pseudomonas aeruginosa.
Chen W, Wang B, Gruber JD, Zhang YM, Davies C
Front Microbiol 2018;9:2244
PubMed ID: 30294316